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PhD candidate (f/m/x) –Gene therapy

102653

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39 h/week
Image Neuherberg near Munich

We are Helmholtz Munich. In a rapidly changing world, we discover breakthrough solutions for better health.

Our research is focused within the areas of metabolic health/diabetes, environmental health, molecular targets and therapies, cell programming and repair, bioengineering, and computational health. We particularly excel in the fields of basic research, bioengineering, artificial intelligence, and technological development.

Through this research, we build the foundations for medical innovation. Together with our partners, we seek to accelerate the transfer of our research, so that laboratory ideas can reach society and improve people’s quality of life at the fastest rate possible.

This is what drives us. Why not join us and make a difference?


The Institute of Experimental Genetics (IEG) aims to further the understanding of mechanisms underlying human diseases' etiology. Metabolic diseases with a focus on diabetes are key areas of research. Experimental set-ups are centered on the mouse as a pre-clinical model organism with direct translation of results to humans.
The group Functional Genetics investigates molecular pathways and pathophysiological events that lead to diabetes and transfer the results into the development of novel strategies for diagnosis, prevention and therapy. As part of our focus on monogenic forms of diabetes, we offer talented candidates (f/m/x) the opportunity to start an exciting PhD project in performing gene therapy on mouse models and evaluating their therapeutic efficacy by in-depth phenotyping.
Supervisors:
Prof. Dr. Dr h.c. mult. Martin Hrabě de Angelis
Dr. Gerhard Przemeck

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Prof. Matthias Tschöp (Dr. Med., Dr. hc.), CEO of Helmholtz Munich:

"We believe that excellent research requires a range of different perspectives. Diverse teams reach better solutions and are more innovative in their research topics.

Establishing our Diversity Management Strategy demonstrates our commitment to ensuring an appreciative company culture based on mutual respect. We are also implementing diversity-sensitive processes throughout our whole organization."

Your tasks

  • Cell culture: In vitro evaluation of gene therapy strategy
  • Animal handling: Transfer of gene therapy products to target tissues and evaluation of their therapeutic efficacy by systemic phenotyping (in collaboration with the German Mouse Clinic)
  • Histology: Morphometric analysis of target organs
  • Omics technology: Comparative transcriptome and proteome analysis

Your profile

  • Appropriate university studies (M. Sc.) in biology or related disciplines that qualifies the candidate to unroll as PhD student at the Technical University Munich (TUM)
  • Solid background in genetics, molecular and cell biology
  • Practical experience with mouse models is highly valued
  • Excellent communication skills in written and spoken English

Benefits

  • Scientific Training: Helmholtz Munich Graduate School
  • Career counseling: Career Center for PhD candidates
  • Recreation: 30 days annual leave, flexi days, plus public holidays
  • Health Promotion: Sports, company doctor, mental health initiatives
  • International Staff Service: Support with the relocation and integration process in Germany
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Since 2005, we hold the TOTAL E-QUALITY award for exemplary action in the sense of an equal-opportunity organizational culture.

Helmholtz Munich is actively committed to diversity and inclusion in practice and is sustainably committed to equality.

The Diversity Charter has set itself the goal of promoting diversity in the world of work. By signing the charter, we commit ourselves to create an appreciative working environment for all employees.

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This position provides the opportunity for you to build specialist knowledge whilst developing key professional experience, both of which will help you to make strides in your scientific career.

Remuneration and social security benefits are based on the German Collective Wage Agreement for Public-Sector Employees at Federal Level (EG 13 50% TV EntgO Bund). In addition, there is also the possibility of receiving an allowance if the applicable conditions are met. The position has an (initial) fixed term of three years but may be extended under certain circumstances.

We are committed to promoting a culture of diversity and welcome applications from talented people regardless of gender, cultural background, nationality, ethnicity, sexual identity, physical abilities, religion or age. Qualified applicants with physical disabilities will be given preference. If you have obtained a university degree abroad, we will require further documents from you regarding the comparability of your degree. Please request the Statement of Comparability for Foreign Higher Education Qualifications as early as possible.

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Interested in applying?

If you have any questions, feel free to contact Dr. Gerhard Przemeck, gerhard.przemeck@helmholtz-munich.de, who will be happy to help.

Your application should include
    • CV
    • Cover letter
    • Degrees/Diplomas/Certificates
    • Contact details for at least two referees

    We are Helmholtz Munich.

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