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Helmholtz Zentrum München is a research center with the mission to discover personalized medical solutions for the prevention and therapy of environmentally triggered diseases and promote a healthier society in a rapidly changing world.

At our institute you will find a scientifically stimulating international environment. Together with renowned scientists and supported by an excellent infrastructure you will have the opportunity to make an important contribution for a healthier society.

The research group for Cell Engineering is one of 11 inter-disciplinary laboratories at the Institute of Biological and Medical Imaging (IBMI) at the Helmholtz Zentrum Muenchen (HMGU) and focuses on developing genetically encodable molecular labels and sensors for innovative imaging schemes primarily fluorescence and optoacoustic imaging. We use protein engineering to develop labels based on our research in photophysics and structure-function relationships. These labels are employed on the level of single mammalian cells as well as whole organisms. We also work on specialized screening, spectroscopy and imaging instrumentation to complement our molecular tools. We are looking for a highly qualified and motivated PhD student (f/m/d) to explore the photophysics of innovative optical labels and develop instrumentation for screening and spectroscopy. Optoacoustic imaging is a novel imaging approach that is currently only little explored in regard to the underlying photophysics of its labels (contrast agents). Our group is focusing on chromophoric proteins but is also interested in synthetic dyes and bio-inspired nano-particles. In all cases, an understanding of photophysics is essential to steer development approaches.

We are looking for a highly motivated

PhD student (f/m/x) to explore the photophysics of innovative optical labels and develop instrumentation for screening and spectroscopy 100623

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Your responsibilities

    The student will work tightly with protein-engineers and chemists in understanding the photophysics by developing next generation instrumentation for the high-throughput characterization of photophysical features in cells and purified protein as well as Optoacoustics imaging devices exploiting those new agents. These technologies will build on advanced optics, e.g. in combination with microfluidics, ultrasound detection and fast data acquisition and processing. The position calls for a high motivation and curiosity, not only to build setups but also link to other disciplines in multidisciplinary projects. The work will give the student the possibility to hone their analytical skills at the interface of technology, data-science and life-science which is typical for many modern research questions. Consequently, the work will be conducted in close collaboration with other interdisciplinary researchers of the Cell Engineering group but also other laboratories of the Technical University Munich (TUM) and HMGU that are leading in the respective research areas, e.g. engineering, data-sciences, cell-biology and bio-medical research.

Your qualifications

  • High motivation, curiosity, and commitment to scientific excellence
  • Master Degree in Physics, Optical-Engineering, Chemistry, Biochemistry, or similar field
  • Background in optical or ultrasound methods
  • Experience in setup building/modification and not only application
  • Skills of problem solving and prototype designing according to unmet specifications
  • Interest in chromophores, photophysics, photochemistry
  • Interest in optical spectroscopy techniques
  • Interest in bio / biomedical applications
  • Team player skills and enthusiasm to work in a multi-disciplinary, collaborative environment
  • Excellent command of the English language

What we offer you

continuous education and training
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work-life balance
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flexible working hours & time off in lieu
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30 days annual leave
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on-site health management service
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Munich, with its numerous lakes and its vicinity to the Alps, is considered to be one of the cities with the best quality of life worldwide. With its first-class universities and world-leading research institutions it offers an intellectually stimulating environment.

Remuneration and social benefits are based on the collective wage agreement for public-sector employees at federal level (EG 13 50% TV EntgO Bund). In addition, there is also the possibility of granting an allowance amounting to 15% if the necessary conditions are fulfilled. The position is (initially) limited to three years, but under certain circumstances an extension can be arranged.

To promote diversity, we welcome applications from talented people regardless of cultural background, nationality, ethnicity, gender and sexual identity, physical abilities, religion and age until . Qualified applicants with physical disabilities will be given preference.
Applicant guidance on the Corona pandemic

Interested?
If you have further questions, simply contact Dr. André C. Stiel email: andre.stiel@helmholtz-muenchen.de tel.: +49 89 3187 3972, who will be happy to be of assistance.
Helmholtz Zentrum München
Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH)
Institute of Biological and Medical Imaging
Ingolstädter Landstraße 1

85764 Neuherberg

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