Our mission as research center: Discover personalized medical solutions for environmentally triggered diseases to promote a healthier society in a rapidly changing world.

The Deng lab at the Institute of Virology at Helmholtz Munich and the Technical University of Munich uses an integrative approach combining single-cell technologies, culture-independent techniques, multi-omics, and machine learning to understand the underlying mechanisms of virome-microbiome interactions and their impact on the human health.

Gut bacteria play a key role in human health by regulating functions, producing essential metabolites, and protecting against pathogens. Imbalances in their composition are linked to multiple human diseases and conditions. While external factors can influence these bacteria, nonspecific changes can lead to unexpected long-term effects. Bacteriophages, or phages, offer a promising solution as they have high specificity, minimizing the risk of harming the gut bacteria community. Therefore, you will work on a project that aims to develop a targeted approach for manipulating the human microbiome for treating dysbiosis associated diseases such as inflammatory bowel disease and colorectal cancer.

Below you can find some of our relevant publications: / / /

PhD in developing targeted approaches for manipulating the human microbiome (f/m/x) 102039

Image Full time
Image Neuherberg near Munich
Image PhD

Your mission

  • Using culture-independent and single-cell approaches to isolate novel phages against multiple causative bacteria
  • Study the interactions between phages and their bacterial host on both population and single-cell levels using multi-omics
  • Developing phage-based therapeutics for diseases such as IBD and CRC and testing their effect using in vivo models

Your qualifications

  • MSc in Microbiology, Molecular Biology, Biotechnology or a related field
  • Being familiar with flow cytometers and cell sorting, qPCR or digital PCR, anaerobic chambers and/or bioreactors
  • Good written and verbal communication skills in English

What we offer you

scientific training at HELENA Graduate School
work-life balance
flexible working hours & time off in lieu
30 days annual leave
on-site health management service
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Image mobile work
Image on-site nursery
Image company pension scheme
Image discounted public transport ticket

Munich, with its numerous lakes and its vicinity to the Alps, is considered to be one of the cities with the best quality of life worldwide. With its first-class universities and world-leading research institutions it offers an intellectually stimulating environment.

This position also provides the opportunity for you to build specialist knowledge and collect significant professional experience, both of which will help advance your scientific career.

Remuneration and social benefits are based on the collective wage agreement for public-sector employees at federal level (EG 13 50% TV EntgO Bund). In addition, there is also the possibility of granting an allowance if the necessary conditions are fulfilled. The position is (initially) limited to three years, but under certain circumstances an extension can be arranged.

To promote diversity, we welcome applications from talented people regardless of gender, cultural background, nationality, ethnicity, sexual identity, physical abilities, religion and age. Qualified applicants with physical disabilities will be given preference.
If you have obtained a university degree abroad, we require further documents from you regarding the recognition of the degree. Please request the recognition as early as possible.

If you have further questions, simply contact Dr. Mohammadali Khan Mirzaei,, who will be happy to be of assistance.
Helmholtz Zentrum München
Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH)
Institute of Virology
Ingolstädter Landstraße 1 

85764 Oberschleißheim

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