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Helmholtz Zentrum München is a research center with the mission to discover personalized medical solutions for the prevention and therapy of environmentally triggered diseases and promote a healthier society in a rapidly changing world.

At our institute you will find a scientifically stimulating international environment. Together with renowned scientists and supported by an excellent infrastructure you will have the opportunity to make an important contribution for a healthier society.

The research group for Cell Engineering is one of 11 inter-disciplinary laboratories at the Institute of Biological and Medical Imaging (IBMI) at the Helmholtz Zentrum Muenchen (HMGU) and focuses on developing genetically encodable molecular labels and sensors for innovative imaging schemes primarily fluorescence and optoacoustic imaging. We develop labels based on strategies of protein engineering building on our research in photophysics and structure-function relationships. The developed molecular tools are employed on the level of single mammalian cells as well as whole organisms.

We are looking for a highly motivated

Postdoc (f/m/x) researching photophysics of protein-based imaging labels and sensors. 100618

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Image Neuherberg near Munich
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Your responsibilities

The candidate will work on studying the mechanisms of photophysical functioning of chromophore-bearing proteins (such as GFP-like, Bacteriophytochromes or Phycobiliproteins) using and developing spectroscopic methods. The gained insight will fuel the development of new labels and sensors on the molecular level. The candidate will bridge between the applications, the technical developments of imaging-setups and the protein engineering and support all approaches with the photophysical insight. One of our main foci are photo-switching proteins. Here the candidate will further explore and exploit their intricate and exciting mechanisms towards driving such proteins towards a use in applications – primarily optoacoustics. The work will be conducted in close collaboration with other laboratories of the Technical University Munich (TUM) and HMGU that are leading in the respective research areas, e.g. setup building or protein structure elucidation. Hence, the position is an exciting interface between basic photophysical research, development of molecular tools as well as imaging.

Your qualifications

  • High motivation, curiosity, and commitment to scientific excellence
  • Master Degree and Ph.D. in Chemistry, Physics, Biochemistry or similar field
  • Background in chromophores, photophysics, photochemistry
  • Experience with excited state photophysics, and photoisomerization processed will be appreciated as well as understanding of (protein-) environmental effects on the photophysical properties of chromophores
  • Experience in optical spectroscopy techniques
  • Interest in imaging
  • Team player skills and enthusiasm to work in a multi-disciplinary, collaborative environment
  • Excellent command of the English language

What we offer you

continuous education and training
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work-life balance
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flexible working hours & time off in lieu
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30 days annual leave
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on-site health management service
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Munich, with its numerous lakes and its vicinity to the Alps, is considered to be one of the cities with the best quality of life worldwide. With its first-class universities and world-leading research institutions it offers an intellectually stimulating environment.

Remuneration and social benefits are based on the collective wage agreement for public-sector employees at federal level (TV EntgO Bund). The position is (initially) limited to 2 years, but under certain circumstances an extension can be arranged.

To promote diversity, we welcome applications from talented people regardless of cultural background, nationality, ethnicity, gender and sexual identity, physical abilities, religion and age until . Qualified applicants with physical disabilities will be given preference. We are looking forward to receiving your comprehensive online application, including your letter of motivation, CV and academic transcripts of records, preferably in English.
Applicant guidance on the Corona pandemic

Interested?
If you have further questions, simply contact Dr. André C. Stiel email: andre.stiel@helmholtz-muenchen.de tel.: +49 89 3187 3972, who will be happy to be of assistance.
Helmholtz Zentrum München
Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH)
Institute of Biological and Medical Imaging
Ingolstädter Landstraße 1

85764 Neuherberg near Munich

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