Helmholtz Munich is a research center with the mission to discover personalized medical solutions for the prevention and therapy of environmentally triggered diseases and promote a healthier society in a rapidly changing world.

Obesity and diabetes have become epidemic over the last 20 years. Altough lots of knowledge has been collected regarding the pathogenesis of these diseases, the intracellular regulatory mechanisms are still not resolved. The group of Anja Zeigerer, located at the Institute for Diabetes and Cancer, investigates the role of membrane trafficking in metabolic homeostasis. The lab is seeking to the next possible time point a highly motivated

Postdoc - Cell biology of liver metabolism (m/f/x) 101294

Image Full time
Image Neuherberg near Munich
Image Postdocs

Your responsibilities

to investigate the function of Rab GTPase in mitochondrial fission and protein secretion during the fasting/feeding transition in the liver. This project is part of collaborative effort with the Munich Cluster of Systems Neurology headed by Prof. Christian Behrends t the Ludwig-Maximilians-University (LMU) Munich.

  • Planning and realization of experimental studies in the areas of cell biology and membrane trafficking with connection to liver physiology of fasting and feeding
  • Biochemical, cell biological and immunofluorescence analysis of cell and tissue samples
  • Primary cell culture of murine and human hepatocytes and analysis of tissues from different mouse models to investigate their contribution to the fasting/feeding switch
  • “Omics” data analysis, graphical documentation and evaluation for conferences, scientific publications and reports

Your qualifications

  • PhD or equivalent level of professional qualification in biochemistry or cell biology
  • Strong theoretical and practical background on intracellular membrane trafficking required
  • Experience with complex methods in molecular biology and biochemistry
  • Knowledge in hepatocellular metabolism and physiology are a plus
  • Experience in primary cell culture, imaging and mouse work
  • High motivation, flexibility as well as innovate and creative thinking are a must
  • A strong academic record, international experience and proficiency in English are required

What we offer you

work-life balance
flexible working hours & working-time models
continuous education and training
30 days annual leave
on-site health management service
Image home office options
Image on-site nursery & holiday care
Image elder care
Image company pension scheme
Image discounted public transport ticket

Munich, with its numerous lakes and its vicinity to the Alps, is considered to be one of the cities with the best quality of life worldwide. With its first-class universities and world-leading research institutions it offers an intellectually stimulating environment.

Provided that the prerequisites are fulfilled, a salary level up to E 13 is possible. Social benefits are based on the collective agreement for the federal public service (TVöD). The position is (initially) limited to three years, under certain circumstances an extension can be arranged.

To promote diversity, we welcome applications from talented people regardless of gender, cultural background, nationality, ethnicity, sexual identity, physical abilities, religion and age. Qualified applicants with physical disabilities will be given preference.
If you have obtained a university degree abroad, we require further documents from you regarding the recognition of the degree. Please request the recognition as early as possible.

If you have further questions, simply contact Miriam Guhl, Tel. +49 89 3187-1046 and Anja Zeigerer, Tel. +49 89 3187-1048, who will be happy to be of assistance.
Helmholtz Zentrum München
Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH)
Institute for Diabetes and Cancer
Ingolstädter Landstraße 1

85764 Oberschleißheim

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