Our mission as research center: Discover personalized medical solutions for environmentally triggered diseases to promote a healthier society in a rapidly changing world.

The primary objective of the Institute of Diabetes and Regeneration Research (IDR) at the Helmholtz Diabetes Center, Helmholtz Munich, is to develop regenerative therapeutic approaches to treat diabetes mellitus - complementary and alternative to the classical immunological and metabolic therapy strategies.

We recently won a JDRF Grant with a project focused on Advancing Stem Cell-Based Therapy for Type 1 Diabetes togheter with the team of of Prof. Matthias Hebrok and Prof. Carolin Daniel from the Helmholtz Munich Diabetes Center and Prof. Eckhard Wolf from the Ludwig Maximilian University of Munich (LMU). The project aims to understand how the immune system’s rejection of stem cell derived islets is mediated and can be prevented in the recipient. The successful candidate will work on optimizing the generation of piPSC-derived beta cells and islets for transplantation into pigs.

To complete our scientific research team starting as soon as possible, we are looking for a highly motivated

Postdoc - Stem Cell-Based Therapy for Type 1 Diabetes (f/m/x) 102122

Image Full time
Image Neuherberg near Munich
Image Postdocs

Your responsibilities

  • In vitro studies: Biochemical, immunohistological, immunofluorescence and molecular biology analyses to study different pancreatic cell subtypes
  • Pig, mouse and human islet cell culture for screening and live cell imaging to dissect molecular and cellular mechanisms
  • Upscaling of differentiation process to provide material for in vivo studies
  • Support in the assessment of immune responses, beta cell function and restoration of normoglycemia over time post transplantation
  • Creation of standard operating procedures (SOPs)

Your qualifications

  • Master and PhD in biology, biochemistry, pharmacology or related subject and high interest in preclinical and translational research
  • Strong background in biochemistry, cellular and molecular biology, pancreas development, islet biology and mouse and human genetic
  • Working experience with immunofluorescence, immunohistochemistry confocal microscopy and stem cell culture and/or primary cells is required
  • Experience with in vivo animal models is a plus
  • Ability to work independently, with high motivation, flexibility and innovative and creative thinking, as well as team spirit and good communication skills
  • Excellent written and spoken English

What we offer you

flexible working hours & working-time models
continuous education and training
30 days annual leave
on-site health management service
Image on-site nursery & holiday care
Image elder care
Image company pension scheme
Image discounted public transport ticket

Munich, with its numerous lakes and its vicinity to the Alps, is considered to be one of the cities with the best quality of life worldwide. With its first-class universities and world-leading research institutions it offers an intellectually stimulating environment.

Provided that the prerequisites are fulfilled, a salary level up to E 13 is possible. Social benefits are based on the collective agreement for the federal public service (TVöD). The position is (initially) limited to two years, under certain circumstances an extension can be arranged.

To promote diversity, we welcome applications from talented people regardless of gender, cultural background, nationality, ethnicity, sexual identity, physical abilities, religion and age. Qualified applicants with physical disabilities will be given preference.
If you have obtained a university degree abroad, we require further documents from you regarding the recognition of the degree. Please request the recognition as early as possible.

If you have further questions, simply contact Mara Catani,, who will be happy to be of assistance.
Helmholtz Zentrum München
Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH)
Institute for Diabetes and Regenerations Research
Ingolstädter Landstraße 1

85764 Oberschleißheim

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