Research technician - type 1 diabetes (f/m/x)
Full time39 hrs/week
Munich
We are Helmholtz Munich. In a rapidly changing world we discover breakthrough solutions for better health.
Our research is focused within the areas of metabolic health/diabetes, environmental health, molecular targets and therapies, cell programming and repair, bioengineering, and computational health. Through this research, we build the foundations for medical innovation. Together with our partners, we seek to accelerate the transfer of our research, so that laboratory ideas can reach society and improve people’s quality of life at the fastest rate possible.
Join us and use your talents and passion as we work together to drive forward scientific progress.
The research focus of the Institute of Diabetes Research lays on understanding the pathogenesis of type 1 diabetes, on identifying mechanisms and predictive markers of the disease, and the translation of findings into clinical trials to prevent type 1 diabetes in humans. The Institute is particularly interested in deciphering the molecular mechanisms of islet autoreactivity, and the interaction of environment, genes, and the immune response. The ultimate goal is to develop therapies for the prevention and cure of islet autoimmunity and diabetes.
The laboratory of Dr. Teresa Rodriguez-Calvo within the Institute of Diabetes Research at Helmholtz Munich, is seeking a Research Technician to join a collaborative group studying type 1 diabetes. We are looking for a highly motivated individual to investigate the pathogenesis of type 1 diabetes in humans. You will have the opportunity to analyze pancreatic tissue sections provided by the Network for Pancreatic Organ Donors with Diabetes (nPOD). You will be part of a collaborative project with the laboratory of Prof. Matthias Mann at Max Planck Institute of Biochemistry. Together, we aim to provide a cell-type resolved proteomic analysis of pancreatic islets of Langerhans at different disease stages.
"Our work is focused on defining and characterizing the hallmarks of type 1 diabetes. We closely collaborate with the Network for Pancreatic Organ Donors with Diabetes (nPOD) to study the human pancreas from deceased donors at different stages of their disease. This has allowed us to discover novel pathological aspects, which have opened new lines of investigation that will shape our understanding of the natural history of type 1 diabetes."
Your tasks
- Perform laboratory techniques such as immunofluorescence staining on tissue sections.
- Acquire images using epifluorescence and confocal microscopes.
- Design, modify and execute protocols.
- Analyze different datasets using image analysis tools.
- Organize and summarize acquired data.
- Contribute to troubleshooting experiments and developing new laboratory processes and technologies relevant to the histological analyses of patient material.
- Keep a record of patient samples and data connected with those samples.
- Take care of general laboratory organization and ordering, as well safety.
The selected candidate will receive general instructions on routine work and detailed instructions on new assignments. Training will be provided.
Your profile
- Completed training as a bio-technical assistant or comparable qualifications (e.g. BTA/CTA/MTA), experience and knowledge.
- Knowledge of histology and related techniques including immunohistochemistry and immunofluorescence and previous experience is required.
- Experience in microscopy (epifluorescence, confocal etc.) is highly desirable.
- Excellent written and verbal communication skills in English is required. Good verbal communication skills in German is an advantage.
- A high degree of computer skills (proficiency using programs such as Microsoft Excel, Power Point, Word etc.) is required.
- Basic knowledge of image analysis software is a plus (QuPath, Fiji, ImageJ).
- Ability to work independently and with others within an outstanding scientific environment.
Benefits
Since 2005, we hold the TOTAL E-QUALITY award for exemplary action in the sense of an equal-opportunity organizational culture.
Helmholtz Munich is actively committed to diversity and inclusion in practice and is sustainably committed to equality.
The Diversity Charter has set itself the goal of promoting diversity in the world of work. By signing the charter, we commit ourselves to create an appreciative working environment for all employees.
If you fulfil all the requirements, you may be eligible for a salary grade of up to E 9. Social benefits are based on the Collective Wage Agreement for Public-Sector Employees (TVöD). The position has an (initial) fixed term of 6 months but may be extended under certain circumstances.
We are committed to promoting a culture of diversity and welcome applications from talented people regardless of gender, cultural background, nationality, ethnicity, sexual identity, physical abilities, religion or age. Qualified applicants with physical disabilities will be given preference. If you have obtained a university degree abroad, we will require further documents from you regarding the comparability of your degree. Please request the Statement of Comparability for Foreign Higher Education Qualifications as early as possible.
