Helmholtz Zentrum München is a research center with the mission to discover personalized medical solutions for the prevention and therapy of environmentally triggered diseases and promote a healthier society in a rapidly changing world.

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The Helmholtz Institute for Metabolic, Obesity and Vascular Research (Helmholtz-Institut für Metabolismus-, Adipositas- und Gefäßforschung, HI-MAG) at the University of Leipzig, aims at uncovering the molecular underpinnings of adipose tissue dysfunction to enable precision therapies for obesity and its co-morbidities, like metabolic and vascular disturbances, using a clinical translational approach. The institute is part of the Helmholtz Diabetes Center and closely linked to the metabolic research activities of the Faculty of Medicine Leipzig.

The newly founded Young Investigator Group "Diet-Induced Metabolic Alterations" headed by Dr. Alexander Jais is looking for a highly motivated

PhD Student in Immuno-Metabolism & Obesity Research at the YIG „Diet-Induced Metabolic Alterations" (f/m/d) 100245

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Your mission

    In the YIG "Diet-Induced Metabolic Alterations", we use different genetic mouse models to decipher the molecular and genetic underpinnings of obesity development. The primary goal of the project is to identify key determinants that promote metabolic health and to validate newly discovered biomarkers that alter both food intake and glucose homeostasis. Our methodology includes for example the isolation of primary cells from adipose tissue, FACS and histological analyses, ex vivo analyses of adipose tissue resident cells and gene/protein expression analyses as well as extensive metabolic phenotyping of genetic mouse models

Your qualification

  • Exceptional students holding a Master’s degree in a relevant field and a strong interest in obesity research, endocrinology and molecular biology
  • Strong background in molecular and cellular biology; hands-on knowledge of immune cell isolation and in vitro culture methods
  • Experience in working with mouse models
  • Outstanding motivation to participate in a competitive research program
  • Excellent English language proficiency, both written and spoken

What we offer you

goal-orientated professional development Image
compatibility of private life & work Image
flexible working hours, flexitime, without core times
30 days vacation per year Image
Image in-house health management
Image Elder Care & further consultation offers
Image company pension scheme
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This position also provides the opportunity for you to build specialist knowledge and collect significant professional experience, both of which will help advance your scientific career.

Remuneration and social benefits are based on the collective wage agreement for public-sector employees at federal level (EG 13 50% TV EntgO Bund). In addition, there is also the possibility of granting an allowance amounting to 15% if the necessary conditions are fulfilled. The position is (initially) limited to three years, but under certain circumstances an extension can be arranged.

To promote diversity, we welcome applications from talented people regardless of cultural background, nationality, ethnicity, gender and sexual identity, physical abilities, religion and age. Qualified applicants with physical disabilities will be given preference.

If you have further questions, please contact Dr. Alexander Jais, 

Your application should include:
• Full curriculum vitae
• A cover letter expressing research interests, along with a brief        summary of your previous projects, including applied techniques
• Certificates of university degrees, academic transcripts with    
  grades in each subject
• Contact information for at least 2 references

Helmholtz Zentrum München
Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH)
Helmholtz-Institut für Metabolismus-, Adipositas- und Gefäßforschung (HI-MAG)
Philipp-Rosenthal-Str. 27

04103 Leipzig

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