Our mission as research center: Discover personalized medical solutions for environmentally triggered diseases to promote a healthier society in a rapidly changing world.

The Helmholtz Pioneer Campus (HPC) founded and funded by Helmholtz Munich stands for the intelligent fusion of biomedical sciences, engineering and digitization. At HPC, top scientific talents from across the globe work together on the development of novel solutions that make a difference in the prevention, diagnosis and treatment of diseases.

The Jasnin Lab uses in situ cryo-electron tomography to explore the molecular architecture of actin systems within unperturbed cellular environments, and elucidate the structural principles governing actin functions across scales.

We are looking for a highly motivated

PhD candidate – In-cell structural biology and biophysics (f/m/x) 101750

Image Full time
Image Neuherberg near Munich
Image PhD

Your mission

  • Have a keen interest in electron microscopy (EM), fluorescence microscopy and actin structure and function
  • Have a keen interest in learning cryo-electron tomography (cryo-ET), correlative cryo-focused ion beam milling (cryo-FIB) sample preparation and image processing
  • Study actin-based processes critical for health and disease using the cryo-ET workflow, from cell sample preparation and optimization to imaging and data analysis
  • Use computational tools for in-cell structural analysis of actin assembly and force generation

Your qualifications

  • Excellent MSc in biology, physics, biochemistry, bioinformatics, or related field of science
  • Knowledge/experience with EM or other structural biology techniques
  • Ability to work in an interdisciplinary (combining structural, molecular, cellular and theoretical approaches) and international team of researchers
  • Fluency in English

Desirable qualifications

  • Experience with cell culture
  • Experience with cryo-EM/ET
  • Experience with (cryo-)FIB/SEM sample preparation
  • Experience with fluorescence microscopy
  • Experience with scientific scripting languages (Python and Matlab)

What we offer you

scientific training at HELENA Graduate School Image
work-life balance Image
flexible working hours
30 days annual leave
on-site health management service
Image career consultation
Image home office options
Image on-site nursery
Image company pension scheme
Image discounted public transport ticket

Munich, with its numerous lakes and its vicinity to the Alps, is considered to be one of the cities with the best quality of life worldwide. With its first-class universities and world-leading research institutions it offers an intellectually stimulating environment.

This position also provides the opportunity for you to build specialist knowledge and collect significant professional experience, both of which will help advance your scientific career.

Remuneration and social benefits are based on the collective wage agreement for public-sector employees at federal level (EG 13 50% TV EntgO Bund). In addition, there is also the possibility of granting an allowance amounting to 15% if the necessary conditions are fulfilled. The position is (initially) limited to three years, but under certain circumstances an extension can be arranged.

To promote diversity, we welcome applications from talented people regardless of gender, cultural background, nationality, ethnicity, sexual identity, physical abilities, religion and age. Qualified applicants with physical disabilities will be given preference.
If you have obtained a university degree abroad, we require further documents from you regarding the recognition of the degree. Please request the recognition as early as possible.

Curious? If you have further questions, simply contact Marion Jasnin, +49 89 3187 43896, who will be happy to be of assistance.

Helmholtz Zentrum München
Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH)
Helmholtz Pioneer Campus
Ingolstädter Landstraße 1

85764 Neuherberg near Munich

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